Deep Dive #7: Gene Circuits

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Overview

Genetic circuits were born from the idea that cells can be thought of as living computers with DNA as its underlying software. A natural extrapolation of this idea is that novel programs from DNA can be engineered to perform user-designated functions. These “programs”, or artificial multigene constructs commonly known as gene circuits, allow cells to make decisions based on the surrounding environment and produce the desired response. In theory, this means that scientists can develop customized sensors and signaling pathways to create novel diagnostics and therapeutics.